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Subject: "Pethidine (Meperidine / Demerol) synthesis???" Archived thread - Read only
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Lobby Opiate Chemistry Topic #304
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herrdoktor click here to view user rating
Member since 10-26-01
43 posts, 1 feedbacks, 2 points
07-25-02, 00:06 AM (EST)
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"Pethidine (Meperidine / Demerol) synthesis???"
 
   I am sure many of us have looked over the synthesis @ the Rhodium for Pethidine, and according to the DEA's website it has been synthesized from time to time in the U.S., and popped up in various areas around the country. They didn't mention (and I have never heard of it) if anyone has ever been arrested for the illicit manufacture of this opioid.

My question to all is this: Is there anyone who has dreamed of actually synthesizing this, and if so how did the dream end? Sucess? Failure? ETC?

So please take the time to share your knowledge, thoughts, and answer the question if you have an answer...

It seems to me that there are other Piperidine synthetic opioids that are even easier with significantly less worry of the evil MPTP byproduct, maybe something like Prodine or Dextromoramide...
Any dreams of working with any of these would be welcome too.

Finally, if you have ever hallucinated an overseas company which will supply useful precoursers for applications such as this, please pm me the information you hallucinated. We wouldn't want such hallucinated info out for all to read. Any info you have which you don't wish to post, pm it to me if you feel comfortable sharing.

We all know this is for info/academic study/dream sharing only, and not a single one of us would ever break the law and attempt anything of this sort.

Thanks!

REaLiTY Is SubJecTivE


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Dr_SteveSenior Somniphile click here to view user rating
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712 posts, 35 feedbacks, 66 points
08-13-02, 03:21 PM (EST)
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1. "RE: Pethidine (Meperidine / Demerol) synthesis???"
 
You should go to your local library and get a copy of PBS's "The case of the frozen addict". It is a story about a person who tried to synthesize meperidine in his basement and turnned up in the local emergency department totally unable to move. Later several other IV drug addicts turnned up the same way. Obviously, his synthesis went wrong!

On a good note, the offending byproduct of his synthesis gave us our first chemical to induce "parkinson syndrome" in animals, specifically monkeys. Before this event, we did not have an animal model of parkinson syndrome. It paved the way to many breakthroughs in the treatment of movement disorders. Unfortunately, I don't think the patient saw it this way.

Make sure you rent a copy. It is a great show!


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herrdoktor click here to view user rating
Member since 10-26-01
43 posts, 1 feedbacks, 2 points
08-22-02, 06:44 AM (EST)
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2. "RE: Pethidine (Meperidine / Demerol) synthesis???"
 
   I am aware of the offending byproducts. If I remember the two possible are MPTP and MPP+.


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